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Whole genome analysis and in vivo safety assessment of probiotic candidate Lactobacillus acidophilus L177

2 Jul 2025

Abstract excerpt

Probiotics, particularly strains of lactic acid bacteria (LAB), are recognized for their beneficial effects on gut health. Lactobacillus acidophilus L177, a promising probiotic strain isolated from canine feces, was evaluated for safety and probiotic properties through whole genome sequencing and a 28-day subacute oral toxicity study in C57BL/6 mice. The toxicity study involved daily administration of L177 at...

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PMID: 40604408
DOI: 10.1186/s12866-025-04099-w

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