Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Visual detection of gene mutations based on isothermal strand-displacement polymerase reaction and lateral flow strip.

Biosensors & bioelectronics - 15 Jan 2012

He Yuqing, Zeng Kang, Zhang Sanquan, Gurung Anant S, Baloda Meenu, Zhang Xibao, Liu Guodong

Abstract excerpt

Here, we describe a simple and sensitive approach for visual detection of gene mutations based on isothermal strand-displacement polymerase reactions (ISDPR) and lateral flow strip (LFS). The concept was first demonstrated by detecting the R156H-mutant gene of keratin 10 in Epidermolytic hyperkeratosis (EHK). In the presence of biotin-modified hairpin DNA and digoxin-modified primer, the R156H-mutant DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biosensing Techniques
Share to DNA-Directed DNA Polymerase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Equipment Design

Share to Hyperkeratosis, Epidermolytic

Share to Microfluidics

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 22133519
DOI: 10.1016/j.bios.2011.10.037
PMCID: PMC3248977

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Visual detection of gene mutations based on isothermal strand-displacement polymerase reaction and lateral flow strip.PMID 22133519Read ↗

Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles.Semantic proximity Read ↗

Liquid biopsy genotyping by a simple lateral flow strip assay with visual detection.Semantic proximity Read ↗

A nanoparticle-based sensor for visual detection of multiple mutations.Semantic proximity Read ↗

Dual toeholds regulated CRISPR-Cas12a sensing platform for ApoE single nucleotide polymorphisms genotyping.Semantic proximity Read ↗

Electroanalysis of single-nucleotide polymorphism by hairpin DNA architectures.Semantic proximity Read ↗

Rapid and Sensitive Visual Detection of Gene Mutations via LIVE-SNP.Semantic proximity Read ↗

Visualised genotyping assay with oral swabs in a closed tube by nested invasive reaction assisted with gold nanoparticle probes.Semantic proximity Read ↗

DNA Genotyping Based on Isothermal Amplification and Colorimetric Detection by Consumer Electronics Devices.Semantic proximity Read ↗

Lateral flow devices for nucleic acid analysis exploiting quantum dots as reporters.Semantic proximity Read ↗

A Lateral Flow Biosensor for the Detection of Single Nucleotide Polymorphisms.Semantic proximity Read ↗

A paper-embedded thermoplastic microdevice integrating additive-enhanced allele-specific amplification and silver nanoparticle-based colorimetric detection for point-of-care testing.Semantic proximity Read ↗

Gold nanoparticles-based biosensing of single nucleotide DNA mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.