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Article

Detection of mutant uromodulin in transgenic mouse harboring a mutant human UMOD gene.

Nucleosides, nucleotides & nucleic acids - 1 Dec 2011

Yasuda Makoto, Kaneko Kiyoko, Kaneko Kiyoka, Hachisu Hiroka, Yamaoka Noriko, Mawatari Ken-ichi, Nakagomi Kazuya, Minoura Norihiko, Hosoyamada Makoto

Abstract excerpt

Uromodulin is the most abundant protein secreted in urine, and the mutated form of the uromodulin gene is associated with uromodulin-associated kidney disease (UAKD). Although uromodulin accumulates in the kidney of UAKD patients, it is unclear whether this is the wildtype or mutant form. In this study, we established a liquid chromatography (LC)-mass spectrometry/mass spectrometry (MS/MS)-based method for the...

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Source

Identifiers

PMID: 22132988
DOI: 10.1080/15257770.2011.611485

Genes

UMOD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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