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Current status and future potential of somatic mutation testing from circulating free DNA in patients with solid tumours

1 Dec 2010

Abstract excerpt

Genetic alterations can determine the natural history of cancer and its treatment response. With further advances in DNA sequencing technology, multiple novel genetic alterations will be discovered which could be exploited as prognostic, predictive and pharmacodynamic biomarkers in the development and use of cancer therapeutics. As such, the importance in clinical practice of efficient and robust somatic mutation...

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PMID: 22132062
DOI: 10.1007/s11568-011-9149-2

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