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Article

Detection of Somatic Copy Number Alterations in Cancer Using Targeted Exome Capture Sequencing

1 Nov 2011

Abstract excerpt

The research community at large is expending considerable resources to sequence the coding region of the genomes of tumors and other human diseases using targeted exome capture (i.e., "whole exome sequencing"). The primary goal of targeted exome sequencing is to identify nonsynonymous mutations that potentially have functional consequences. Here, we demonstrate that whole-exome sequencing data can also be...

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PMID: 22131877
DOI: 10.1593/neo.111252

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