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Hamuramicin C, a Cytotoxic Bicyclic Macrolide Isolated from a Wasp Gut Bacterium

1 Apr 2022

Abstract excerpt

A new bicyclic macrolide, hamuramicin C ( 1 ), was isolated from Streptomyces sp. MBP16, a gut bacterial strain of the wasp Vespa crabro flavofasciata . Its 22-membered macrocyclic lactone structure was determined by NMR and mass spectrometry. The relative configurations of hamuramicin C ( 1 ) were assigned by J -based configuration analysis utilizing 1 H rotating frame Overhauser effect spectroscopy and...

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PMID: 35362983
DOI: 10.1021/acs.jnatprod.1c01075

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