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Article

Rare variants, common markers: synthetic association and beyond.

Genetic epidemiology - 1 Jan 2011

Kent Jack W

Abstract excerpt

The phenomenon of synthetic association raises the possibility that common variant genetic markers may be coupled with functional rare variants sufficiently often to allow the rare variants to be tagged by the common ones. Using human exome sequence data from the 1000 Genomes Project, two investigative teams in Group 12 of Genetic Analysis Workshop 17 found that stochastic coupling between rare and common...

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Identifiers

PMID: 22128064
DOI: 10.1002/gepi.20655
PMCID: PMC3260649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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