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Article

Interleukin-6 gene promoter methylation in rheumatoid arthritis and chronic periodontitis.

Journal of periodontology - 1 Jul 2012

Ishida Kohei, Kobayashi Tetsuo, Ito Satoshi, Komatsu Yasutaka, Yokoyama Tomoko, Okada Moe, Abe Asami, Murasawa Akira, Yoshie Hiromasa

Abstract excerpt

BACKGROUND: Methylation status of the cytokine genes may play a role in the pathogenesis of inflammatory diseases, such as rheumatoid arthritis (RA) and chronic periodontitis (CP). This study was undertaken to evaluate whether the DNA methylation profile of the interleukin-6 (IL-6) gene promoter was unique to individuals with RA and CP. METHODS: The study participants consisted of 30 patients with RA, 30 patients...

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Identifiers

PMID: 22122521
DOI: 10.1902/jop.2011.110356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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