Article
Interleukin-6 receptor gene polymorphisms and periodontitis in a non-smoking Japanese population.
Journal of clinical periodontology - 1 Oct 2006
Galicia Johnah C, Tai Hideaki, Komatsu Yasutaka, Shimada Yasuko, Ikezawa Ikuyo, Yoshie Hiromasa
Abstract excerpt
AIM: The indispensable role of interleukin-6 receptor (IL-6R) in regulating IL-6 responses has been clearly established. We have previously reported that IL6R polymorphisms strongly influenced the serum levels of soluble IL-6R. In this study, we investigated the association between these genetic variations and periodontitis. MATERIAL AND METHODS: Among the seven novel IL6R single-nucleotide polymorphisms (SNPs)...
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