Influence of sex on susceptibility in the Theiler's murine encephalomyelitis virus model for multiple sclerosis.

doi:10.1016/0165-5728(90)90143-b

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Article

Influence of sex on susceptibility in the Theiler's murine encephalomyelitis virus model for multiple sclerosis.

Journal of neuroimmunology - 1 Jan 2000

Kappel C A, Melvold R W, Kim B S

Abstract excerpt

Multiple sclerosis (MS) is a demyelinating disease in humans which affects females more frequently than males. Theiler's murine encephalomyelitis virus (TMEV) induces demyelination similar to human MS in susceptible strains of mice after intracerebral inoculation. In this paper we report that sex...

Topics

Animals
Demyelinating Diseases
Disease Models, Animal
Disease Susceptibility
Genotype
H-2 Antigens
Maus Elberfeld virus
Mice
Mice, Inbred Strains
Multiple Sclerosis
Sex Factors

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