Article
Influence of sex on susceptibility in the Theiler's murine encephalomyelitis virus model for multiple sclerosis.
Journal of neuroimmunology - 1 Jan 2000
Kappel C A, Melvold R W, Kim B S
Abstract excerpt
Multiple sclerosis (MS) is a demyelinating disease in humans which affects females more frequently than males. Theiler's murine encephalomyelitis virus (TMEV) induces demyelination similar to human MS in susceptible strains of mice after intracerebral inoculation. In this paper we report that sex influences susceptibility to TMEV-induced demyelination in certain genotypes derived from C57L/J and SJL/J or SWR/J...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
