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Article

Sex chromosome contributions to sex differences in multiple sclerosis susceptibility and progression

1 Jan 2018

Abstract excerpt

BACKGROUND: Why are women more susceptible to multiple sclerosis, but men have worse disability progression? Sex differences in disease may be due to sex hormones, sex chromosomes, or both. OBJECTIVE: Determine whether differences in sex chromosomes can contribute to sex differences in multiple sclerosis using experimental autoimmune encephalomyelitis. METHODS: Sex chromosome transgenic mice, which permit the...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Genetic Associations and Epidemiology
Share to Sex and Gender in Healthcare

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29307297
DOI: 10.1177/1352458517737394

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