UNC13A is a modifier of survival in amyotrophic lateral sclerosis.

doi:10.1016/j.neurobiolaging.2011.10.029

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Article

UNC13A is a modifier of survival in amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Mar 2012

Diekstra Frank P, van Vught Paul W J, van Rheenen Wouter, Koppers Max, Pasterkamp R Jeroen, van Es Michael A, Schelhaas Helenius J, de Visser Marianne, Robberecht Wim, Van Damme Philip, Andersen Peter M, van den Berg Leonard H, Veldink Jan H

Abstract excerpt

A large genome-wide screen in patients with sporadic amyotrophic lateral sclerosis (ALS) showed that the common variant rs12608932 in gene UNC13A was associated with disease susceptibility. UNC13A regulates the release of neurotransmitters, including glutamate. Genetic risk factors that, in addit...

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PMID: 22118904
DOI: 10.1016/j.neurobiolaging.2011.10.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22118904-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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