Article
Hundreds of putatively functional small open reading frames in Drosophila.
Genome biology - 25 Nov 2011
Ladoukakis Emmanuel, Pereira Vini, Magny Emile G, Eyre-Walker Adam, Couso Juan Pablo
Abstract excerpt
BACKGROUND: The relationship between DNA sequence and encoded information is still an unsolved puzzle. The number of protein-coding genes in higher eukaryotes identified by genome projects is lower than was expected, while a considerable amount of putatively non-coding transcription has been detected. Functional small open reading frames (smORFs) are known to exist in several organisms. However, coding sequence...
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