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Article

2245G/A polymorphism of the receptor for advanced glycation end-products (RAGE) gene is associated with diabetic retinopathy in the Malaysian population.

The British journal of ophthalmology - 1 Feb 2012

Ng Zhi Xiang, Kuppusamy Umah Rani, Tajunisah Iqbal, Fong Kenneth Choong Sian, Koay Adrian Choon Aun, Chua Kek Heng

Abstract excerpt

BACKGROUND/AIMS: The receptor for advanced glycation end-products (RAGE) has been implicated in the pathogenesis of diabetic microvascular complications. The aim of this study was to investigate the association between 2245G/A gene polymorphism of the RAGE gene and retinopathy in Malaysian type 2 diabetic patients. METHODS: 342 unrelated type 2 diabetic patients (171 with retinopathy (DR), 171 without retinopathy...

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Identifiers

PMID: 22116960
DOI: 10.1136/bjophthalmol-2011-300658
PMCID: PMC3261748

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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