Article
Association of candidate genes (ALR2, RAGE, and VEGF) polymorphisms with diabetic retinopathy in type 2 diabetic patients of Khyber Pakhtunkhwa, Pakistan.
Molecular biology reports - 1 Jan 2023
Jehanzeb Mamoona, Khan Najeeb Ullah, Hussain Mahfooz, Subrina Jesmin, Ayub Shahid, Mustafa Adeela
Abstract excerpt
AIM: To evaluate the aldose reductase (ALR2, rs759853), receptor for advanced glycation end products (RAGE, rs2070600), and vascular endothelial growth factor (VEGF, rs833061) association with diabetic retinopathy in type 2 diabetic patients of Khyber Pakhtunkhwa population. METHODS: A case-control study was conducted on a total of 550 subjects consisting of 186 with diabetic retinopathy (DR) having type 2...
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