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Article

GLUT10 is required for the development of the cardiovascular system and the notochord and connects mitochondrial function to TGFβ signaling.

Human molecular genetics - 15 Mar 2012

Willaert Andy, Khatri Sandeep, Callewaert Bert L, Coucke Paul J, Crosby Seth D, Lee Joseph G H, Davis Elaine C, Shiva Sruti, Tsang Michael, De Paepe Anne, Urban Zsolt

Abstract excerpt

Growth factor signaling results in dramatic phenotypic changes in cells, which require commensurate alterations in cellular metabolism. Mutations in SLC2A10/GLUT10, a member of the facilitative glucose transporter family, are associated with altered transforming growth factor-β (TGFβ) signaling in patients with arterial tortuosity syndrome (ATS). The objective of this work was to test whether SLC2A10/GLUT10 can...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22116938
DOI: 10.1093/hmg/ddr555
PMCID: PMC3284116

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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