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Article

Mutations in the SLC2A10 gene cause arterial abnormalities in mice.

Cardiovascular research - 1 Feb 2009

Cheng Chao-Hung, Kikuchi Tateki, Chen Yen-Hui, Sabbagha Nagham George Abd-Al-Ahad, Lee Yi-Ching, Pan Huei-Ju, Chang Chen, Chen Yuan-Tsong

Abstract excerpt

AIMS: Glucose transporter 10 (GLUT10), encoded by the SLC2A10 gene, is a member of the class III facilitative glucose transporter family. Mutations in the SLC2A10 gene cause arterial tortuosity syndrome (ATS) in humans. To further study the pathogenesis of the disease, we generated mice carrying GLUT10 mutations. METHODS AND RESULTS: Using a gene-driven N-ethyl-N-nitrosourea (ENU)-mutagenesis approach, we...

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PMID: 19028722
DOI: 10.1093/cvr/cvn319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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