Article
Trigger factor depletion or overproduction causes defective cell division but does not block protein export.
Journal of bacteriology - 1 Oct 1990
Guthrie B, Wickner W
Abstract excerpt
Trigger factor is an abundant cytosolic protein of Escherichia coli which can stabilize proOmpA for in vitro translocation across inner membrane vesicles. The gene encoding E. coli trigger factor was isolated and sequenced, allowing construction of strains in which the expression of trigger factor is readily regulated. We found no defect in the in vivo rate of synthesis or secretion of proOmpA in trigger...
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