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Article

The effects of single and combined antibiotics on the growth of Legionella pneumophila using time-kill studies.

The Journal of antimicrobial chemotherapy - 1 Jul 1990

Barker J E, Farrell I D

Abstract excerpt

The combinations of erythromycin with rifampicin, with ciprofloxacin or with amoxycillin, and ciprofloxacin plus rifampicin were tested by the time-kill curve method to assess their bactericidal activity against Legionella pneumophila. Rifampicin-resistant strains were found in broth cultures of the micro-organism even before exposure to the drug. In the presence of MBCs of rifampicin, the sensitive organisms...

Topics

Amoxicillin
Anti-Bacterial Agents
Ciprofloxacin
Culture Media
Drug Resistance, Microbial
Drug Therapy, Combination
Erythromycin
Legionella
Microbial Sensitivity Tests
Mutation
Rifampin

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Identifiers

PMID: 2211446
DOI: 10.1093/jac/26.1.45

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2211446-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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