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Article

Identification of adeno-associated viral vectors suitable for intestinal gene delivery and modulation of experimental colitis

24 Nov 2011

Abstract excerpt

Effective gene transfer with sustained gene expression is an important adjunct to the study of intestinal inflammation and future therapy in inflammatory bowel disease. Recombinant adeno-associated virus (AAV) vectors are ideal for gene transfer and long-term transgene expression. The purpose of our study was to identify optimal AAV pseudotypes for transduction of the epithelium in the small intestine and colon,...

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Share to Viral gastroenteritis research and epidemiology
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PMID: 22114116
DOI: 10.1152/ajpgi.00562.2010

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