Article
The association analysis of RELN and GRM8 genes with autistic spectrum disorder in Chinese Han population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2008
Li Hui, Li Yun, Shao Jie, Li Rong, Qin Yufeng, Xie Chunhong, Zhao Zhengyan
Abstract excerpt
The region on chromosome 7q stands out as the region of suggestive linkage to aetiology of autism with the greatest concordance in many independent genome-wide scans. RELN and GRM8, the two genes selected in this study, are located within this region. The protein products of both genes are considered to play a pivotal role in the development of the central nervous system. In addition, biochemical and...
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