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Article

The influence of genetic and environmental factors among MDMA users in cognitive performance.

PloS one - 1 Jan 2011

Cuyàs Elisabet, Verdejo-García Antonio, Fagundo Ana Beatriz, Khymenets Olha, Rodríguez Joan, Cuenca Aida, de Sola Llopis Susana, Langohr Klaus, Peña-Casanova Jordi, Torrens Marta, Martín-Santos Rocío, Farré Magí, de la Torre Rafael

Abstract excerpt

This study is aimed to clarify the association between MDMA cumulative use and cognitive dysfunction, and the potential role of candidate genetic polymorphisms in explaining individual differences in the cognitive effects of MDMA. Gene polymorphisms related to reduced serotonin function, poor competency of executive control and memory consolidation systems, and high enzymatic activity linked to bioactivation of...

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Identifiers

PMID: 22110616
DOI: 10.1371/journal.pone.0027206
PMCID: PMC3217947

Genes

COMT
BDNF

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