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Article

Mechanism of histone methylation catalyzed by protein lysine methyltransferase SET7/9 and origin of product specificity.

Proceedings of the National Academy of Sciences of the United States of America - 22 May 2007

Guo Hao-Bo, Guo Hong

Abstract excerpt

Methylation of certain lysine residues in the N-terminal tails of core histone proteins in nucleosome is of fundamental importance in the regulation of chromatin structure and gene expression. Such histone modification is catalyzed by protein lysine methyltransferases (PKMTs). PKMTs contain a con...

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Identifiers

PMID: 17517655
DOI: 10.1073/pnas.0702981104
PMCID: PMC1885582

Genes

SET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17517655-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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