Article
PRSS1 intron mutations in patients with pancreatic cancer and chronic pancreatitis.
Molecular medicine reports - 1 Feb 2012
Gao Feng, Liu Qi-Cai, Zhang Sheng, Zhuang Ze-Hao, Lin Cai-Zhu, Lin Xin-Hua
Abstract excerpt
Genetic risk factors of chronic pancreatitis (CP) have been identified and a number of studies have found that CP can lead to pancreatic cancer. Therefore, the detection of pancreatitis-associated gene mutations can aid the pancreatic cancer diagnostic process. Mutations in three genes, the cationic trypsinogen (PRSS1) gene, the cystic fibrosis transmembrane conductance regulator (CFTR) gene and the pancreatic...
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