Article
Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.
BMC medical genetics - 22 Nov 2011
Kelempisioti Anthi, Eskola Pasi J, Okuloff Annaleena, Karjalainen Ulla, Takatalo Jani, Daavittila Iita, Niinimäki Jaakko, Sequeiros Roberto B, Tervonen Osmo, Solovieva Svetlana, Kao Patrick Y P, Song You-Qiang, Cheung Kenneth M C, Chan Danny, Ala-Kokko Leena, Järvelin Marjo-Riitta, Karppinen Jaro, Männikkö Minna
Abstract excerpt
BACKGROUND: Disc degeneration (DD) is a common condition that progresses with aging. Although the events leading to DD are not well understood, a significant genetic influence has been found. This study was undertaken to assess the association between relevant candidate gene polymorphisms and moderate DD in a well-defined and characterized cohort of young adults. Focusing on young age can be valuable in...
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