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Article

KCNQ4 K(+) channels tune mechanoreceptors for normal touch sensation in mouse and man.

Nature neuroscience - 20 Nov 2011

Heidenreich Matthias, Lechner Stefan G, Vardanyan Vitya, Wetzel Christiane, Cremers Cor W, De Leenheer Els M, Aránguez Gracia, Moreno-Pelayo Miguel Ángel, Jentsch Thomas J, Lewin Gary R

Abstract excerpt

Mutations inactivating the potassium channel KCNQ4 (K(v)7.4) lead to deafness in humans and mice. In addition to its expression in mechanosensitive hair cells of the inner ear, KCNQ4 is found in the auditory pathway and in trigeminal nuclei that convey somatosensory information. We have now detec...

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Source

Identifiers

PMID: 22101641
DOI: 10.1038/nn.2985

Genes

KCNQ4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22101641-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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