Article
IL28B polymorphisms are markers of therapy response and are influenced by genetic ancestry in chronic hepatitis C patients from an admixed population.
Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2012
Cavalcante Lourianne N, Abe-Sandes Kiyoko, Angelo Ana Luiza D, Machado Taisa M B, Lemaire Denise C, Mendes Carlos M C, Pinho João R, Malta Fernanda, Lyra Luiz G C, Lyra André C
Abstract excerpt
BACKGROUND: IL28B polymorphisms are predictors of therapy response in hepatitis C virus (HCV) patients. We do not know whether they are markers of treatment response in admixed populations or not. AIMS: To determine whether IL28B polymorphisms are predictors of therapy response in patients with HCV from an admixed population and are influenced by genetic ancestry. METHODS: rs12979860 and rs8099917 were genotyped...
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