Article
Meta-analysis: IL-28B genotype and sustained viral clearance in HCV genotype 1 patients.
Alimentary pharmacology & therapeutics - 1 Jul 2012
Rangnekar A S, Fontana R J
Abstract excerpt
BACKGROUND: Polymorphisms in the IL-28B region are a strong predictor of sustained virologic response (SVR) in individual studies of HCV genotype 1 patients receiving peginterferon (pegIFN) and ribavirin. AIM: To obtain a pooled odds ratio (OR) of SVR in patients of varying race with the favourable IL-28B genotype compared to those with the unfavourable genotype. METHODS: A literature search was conducted using...
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