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Article

Evidence for more than one Parkinson's disease-associated variant within the HLA region.

PloS one - 1 Jan 2011

Hill-Burns Erin M, Factor Stewart A, Zabetian Cyrus P, Thomson Glenys, Payami Haydeh

Abstract excerpt

Parkinson's disease (PD) was recently found to be associated with HLA in a genome-wide association study (GWAS). Follow-up GWAS's replicated the PD-HLA association but their top hits differ. Do the different hits tag the same locus or is there more than one PD-associated variant within HLA? We show that the top GWAS hits are not correlated with each other (0.00≤r(2)≤0.15). Using our GWAS (2000 cases, 1986...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22096524
DOI: 10.1371/journal.pone.0027109
PMCID: PMC3212531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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