Article
Human platelets antigens influence the viral load of platelets after the interaction of the platelets with HCV and HIV in vitro.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000
Grotto Rejane Maria Tommasini, Cantão Natália Mirele, Padovani Juliana Lara, Souza Lenice do Rosário de, Silva Giovanni Faria, Ferrasi Adriana Camargo, Pardini Maria Inês de Moura Campos
Abstract excerpt
INTRODUCTION: In this study, we evaluated hepatitis C virus (HCV) and human immunodeficiency virus (HIV) - platelet interactions in vitro as well as human platelets antigen (HPA) polymorphisms. METHODS: Platelets were obtained from 100 healthy HPA-genotyped volunteer donors and incubated with HIV or HCV. The viral load after in vitro exposure was detected. RESULTS: The viral load in the platelets after exposure...
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