Article
Integrin alpha V polymorphisms and haplotypes in a Korean population are associated with susceptibility to chronic hepatitis and hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2009
Lee Seung Ku, Kim Min-Ho, Cheong Jae Youn, Cho Sung Won, Yang Song-Ju, Kwack Kyubum
Abstract excerpt
BACKGROUND/AIMS: Integrins are cell surface receptors for extracellular matrix (ECM) proteins that initiate signalling pathways that modulate proliferation, survival, invasion or metastasis. Consequently, integrins are potential targets for the treatment of cancer. In this study, we investigated whether single nucleotide polymorphisms (SNPs) in integrin alpha(V) (ITGAV) in a Korean population were associated with...
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