Article
Fine-scale estimation of location of birth from genome-wide single-nucleotide polymorphism data.
Genetics - 1 Feb 2012
Hoggart Clive J, O'Reilly Paul F, Kaakinen Marika, Zhang Weihua, Chambers John C, Kooner Jaspal S, Coin Lachlan J M, Jarvelin Marjo-Riitta
Abstract excerpt
Systematic nonrandom mating in populations results in genetic stratification and is predominantly caused by geographic separation, providing the opportunity to infer individuals' birthplace from genetic data. Such inference has been demonstrated for individuals' country of birth, but here we use data from the Northern Finland Birth Cohort 1966 (NFBC1966) to investigate the characteristics of genetic structure...
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