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Article

Posttranslational modifications control FoxO3 activity during denervation.

American journal of physiology. Cell physiology - 1 Feb 2012

Bertaggia Enrico, Coletto Luisa, Sandri Marco

Abstract excerpt

Loss of muscle mass occurs in a variety of diseases including cancer, chronic heart failure, AIDS, diabetes, and renal failure, often aggravating pathological progression. The atrophy process is controlled by a transcriptional program that regulates the expression of a subset of genes named atrophy-related genes. The Forkhead Box O (FoxO) family of transcription factors plays a critical role in the atrophy...

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Source

Identifiers

PMID: 22094330
DOI: 10.1152/ajpcell.00142.2011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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