Article
KRAS and BRAF mutation analysis from liquid-based cytology brushings of colorectal carcinoma in comparison with formalin-fixed, paraffin-embedded tissue.
Anticancer research - 1 Jun 2010
Spathis Aris, Georgoulakis John, Foukas Periklis, Kefala Maria, Leventakos Konstantinos, Machairas Anastasios, Panayiotides Ioannis, Karakitsos Petros
Abstract excerpt
Real-time PCR-based molecular diagnostic techniques were used for the comparative identification of the most common KRAS and BRAF mutations from methanol liquid-based cytology samples and matched, formalin-fixed and paraffin-embedded tissue samples. Methanol-based fixation and preservation of brushing samples of colorectal carcinomas could contribute to sample collection, short-term storage and subsequent...
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