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Article

Hepatitis B vaccine effectiveness in the face of global HBV genotype diversity.

Expert review of vaccines - 1 Dec 2011

Cassidy Adrian, Mossman Sally, Olivieri Antonio, De Ridder Marc, Leroux-Roels Geert

Abstract excerpt

Recombinant hepatitis B vaccines are of the A2 genotype; one of ten known genotypes whose distribution varies globally. Reports of rare HBV infections in blood donors with an imbalance of non-A2 genotype HBV in vaccinated subjects have raised questions about the cross-protection afforded by HBV-A2 vaccines. Infections in HBV vaccinees were asymptomatic and transient, indicating that vaccination prevented clinical...

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Source

Identifiers

PMID: 22085174
DOI: 10.1586/erv.11.151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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