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Article

Validation of cross-genotype neutralization by hepatitis B virus-specific monoclonal antibodies by in vitro and in vivo infection.

PloS one - 1 Jan 2015

Hamada-Tsutsumi Susumu, Iio Etsuko, Watanabe Tsunamasa, Murakami Shuko, Isogawa Masanori, Iijima Sayuki, Inoue Takako, Matsunami Kayoko, Tajiri Kazuto, Ozawa Tatsuhiko, Kishi Hiroyuki, Muraguchi Atsushi, Joh Takashi, Tanaka Yasuhito

Abstract excerpt

Vaccines based on hepatitis B virus (HBV) genotype A have been used worldwide for immunoprophylaxis and are thought to prevent infections by non-A HBV strains effectively, whereas, vaccines generated from genotype C have been used in several Asian countries, including Japan and Korea, where HBV genotype C is prevalent. However, acute hepatitis B caused by HBV genotype A infection has been increasing in Japan and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25693196
DOI: 10.1371/journal.pone.0118062
PMCID: PMC4333126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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