Article
Common variants in FTO are not significantly associated with obesity-related phenotypes among Samoans of Polynesia.
Annals of human genetics - 1 Jan 2012
Karns Rebekah, Viali Satupaitea, Tuitele John, Sun Guangyun, Cheng Hong, Weeks Daniel E, McGarvey Stephen T, Deka Ranjan
Abstract excerpt
The association between obesity and the fat mass and obesity-associated (FTO) gene has been widely replicated among Caucasian populations. The limited number of studies assessing its significance in Asian populations has been somewhat conflicting. We performed a genetic association study of 51 tagging, genome-wide association studies, and imputed single nucleotide polymorphisms with 12 measures of adiposity and...
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