Article
An MDBP site in the first intron of the human c-myc gene.
Cancer research - 1 Nov 1990
Zhang X Y, Supakar P C, Wu K Z, Ehrlich K C, Ehrlich M
Abstract excerpt
The expression of the human c-myc protooncogene is subject to many levels and types of control. Evidence suggests that regulation of the expression of this gene involves elements within the gene as well as those upstream from the gene. We show that a ubiquitous mammalian sequence-specific DNA-binding protein, MDBP, binds specifically to a site in the beginning of the first intron of this gene. This protein, which...
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