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Article

Together yes, but not coupled: new insights into the roles of RAD51 and DMC1 in plant meiotic recombination.

The Plant journal : for cell and molecular biology - 1 Mar 2012

Pradillo Mónica, López Eva, Linacero Rosario, Romero Concepción, Cuñado Nieves, Sánchez-Morán Eugenio, Santos Juan L

Abstract excerpt

The eukaryotic recombinases RAD51 and DMC1 are essential for DNA strand-exchange between homologous chromosomes during meiosis. RAD51 is also expressed during mitosis, and mediates homologous recombination (HR) between sister chromatids. It has been suggested that DMC1 might be involved in the switch from intersister chromatid recombination in somatic cells to interhomolog meiotic recombination. At meiosis, the...

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Source

Identifiers

PMID: 22066484
DOI: 10.1111/j.1365-313X.2011.04845.x

Genes

RAD51
DMC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Together yes, but not coupled: new insights into the roles of RAD51 and DMC1 in plant meiotic recombination.PMID 22066484Read ↗

The AtRAD51C gene is required for normal meiotic chromosome synapsis and double-stranded break repair in Arabidopsis.Semantic proximity Read ↗

The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis.Semantic proximity Read ↗

DMC1 attenuates RAD51-mediated recombination in ArabidopsisSemantic proximity Read ↗

Arabidopsis RAD51C gene is important for homologous recombination in meiosis and mitosis.Semantic proximity Read ↗

The interplay of RecA-related proteins and the MND1-HOP2 complex during meiosis in Arabidopsis thaliana.Semantic proximity Read ↗

Differing requirements for the Arabidopsis Rad51 paralogs in meiosis and DNA repair.Semantic proximity Read ↗

MCM8 is required for a pathway of meiotic double-strand break repair independent of DMC1 in Arabidopsis thaliana.Semantic proximity Read ↗

DNA-binding site II is required for RAD51 recombinogenic activity in Arabidopsis thaliana.Semantic proximity Read ↗

BRCA2 is a mediator of RAD51- and DMC1-facilitated homologous recombination in Arabidopsis thaliana.Semantic proximity Read ↗

The Arabidopsis thaliana MND1 homologue plays a key role in meiotic homologous pairing, synapsis and recombination.Semantic proximity Read ↗

Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair of double-strand breaks.Semantic proximity Read ↗

RAD54 is essential for RAD51-mediated repair of meiotic DSB in ArabidopsisSemantic proximity Read ↗

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