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Article

Two-stage binding of SecA to the bacterial translocon regulates ribosome-translocon interaction.

The Journal of biological chemistry - 17 Oct 2003

Zito Christopher R, Oliver Donald

Abstract excerpt

The bacterial translocon interacts with both SecA-bound preproteins and nascent chain-ribosome complexes during Sec and signal recognition particle-dependent protein translocation, respectively. In their inactive state, translocons are saturated with ribosomes and SecA protein, reflecting the inherent affinity of these components for one another. We found that SecA and ribosomes are bound simultaneously and...

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Identifiers

PMID: 12907673
DOI: 10.1074/jbc.M308025200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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