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Article

Both pre- and postsynaptic activity of Nsf prevents degeneration of hair-cell synapses.

PloS one - 1 Jan 2011

Mo Weike, Nicolson Teresa

Abstract excerpt

Vesicle fusion contributes to the maintenance of synapses in the nervous system by mediating synaptic transmission, release of neurotrophic factors, and trafficking of membrane receptors. N-ethylmaleimide-sensitive factor (NSF) is indispensible for dissociation of the SNARE-complex following vesicle fusion. Although NSF function has been characterized extensively in vitro, the in vivo role of NSF in vertebrate...

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Source

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Identifiers

PMID: 22073277
DOI: 10.1371/journal.pone.0027146
PMCID: PMC3207842

Genes

BDNF
NSF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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