Article
Self-reported lower respiratory tract infections and development of islet autoimmunity in children with the type 1 diabetes high-risk HLA genotype: the MIDIA study.
Diabetes/metabolism research and reviews - 1 Nov 2011
Rasmussen Trond, Witsø Elisabet, Tapia German, Stene Lars C, Rønningen Kjersti S
Abstract excerpt
AIM: To test whether self-reported lower respiratory tract infections in early infancy predicted risk for islet autoimmunity in genetically predisposed children. METHODS: The environmental triggers for type 1 diabetes (MIDIA) study recruited newborns in Norway to identify those with the human leukocyte antigen high-risk genotype DR4-DQ8/DR3-DQ2. Of 46 939 newborns genotyped, 1003 (2.1%) carried the high-risk...
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