Article
Infections in the first year of life and development of beta cell autoimmunity and clinical type 1 diabetes in high-risk individuals: the TRIGR cohort.
Diabetologia - 1 Dec 2022
Kordonouri Olga, Cuthbertson David, Belteky Malin, Aschemeier-Fuchs Bärbel, White Neil H, Cummings Elisabeth, Knip Mikael, Ludvigsson Johnny
Abstract excerpt
AIMS/HYPOTHESIS: Accumulated data suggest that infections in early life contribute to the development of type 1 diabetes. Using data from the Trial to Reduce IDDM in the Genetically at Risk (TRIGR), we set out to assess whether children who later developed diabetes-related autoantibodies and/or clinical type 1 diabetes had different exposure to infections early in life compared with those who did not. METHODS: A...
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