Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.

doi:10.1001/jamapediatrics.2017.2905

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Article

Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.

JAMA pediatrics - 1 Dec 2017

Kemppainen Kaisa M, Vehik Kendra, Lynch Kristian F, Larsson Helena Elding, Canepa Ronald J, Simell Ville, Koletzko Sibylle, Liu Edwin, Simell Olli G, Toppari Jorma, Ziegler Anette G, Rewers Marian J, Lernmark Åke, Hagopian William A, She Jin-Xiong, Akolkar Beena, Schatz Desmond A, Atkinson Mark A, Blaser Martin J, Krischer Jeffrey P, Hyöty Heikki, Agardh Daniel, Triplett Eric W

Abstract excerpt

Importance: Evidence is lacking regarding the consequences of antibiotic use in early life and the risk of certain autoimmune diseases. Objective: To test the association between early-life antibiotic use and islet or celiac disease (CD) autoimmunity in genetically at-risk children prospectively followed up for type 1 diabetes (T1D) or CD. Design, Setting, and Participants: HLA-genotyped newborns from Finland,...

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Identifiers

PMID: 29052687
DOI: 10.1001/jamapediatrics.2017.2905
PMCID: PMC5716863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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