Article
Genotypic and phenotypic variation of Lewis antigen expression in geographically diverse Helicobacter pylori isolates.
Helicobacter - 1 Dec 2011
Pohl Mary Ann, Zhang William, Shah Sunny N, Sanabria-Valentín Edgardo L, Perez-Perez Guillermo I, Blaser Martin J
Abstract excerpt
BACKGROUND: Helicobacter pylori are a persistent colonizer of the human gastric mucosa, which can lead to the development of peptic ulcer disease and gastric adenocarcinomas. However, H. pylori can asymptomatically colonize a host for years. One factor that has been hypothesized to contribute to such persistence is the production of Lewis (Le) antigens in the lipopolysaccharide layer of the bacterial outer...
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