Article
Association of Lewis and Secretor gene polymorphisms and Helicobacter pylori seropositivity among Japanese-Brazilians.
Journal of gastroenterology - 1 Aug 2004
Oba-Shinjo Sueli Mieko, Uno Miyuki, Ito Lucy Sayuri, Shinjo Samuel Katsuyuki, Marie Suely Kazue Nagahashi, Hamajima Nobuyuki
Abstract excerpt
BACKGROUND: Secretor ( Se) and Lewis ( Le) genes are involved in the synthesis of Lewis b (Le(b)) and type I antigens throughout the body, especially in the epithelial cells of gastric mucosa. Helicobacter pylori can attach to the gastric epithelial cells with the blood group antigen-binding adhesin, which binds to Le(b) or H type I carbohydrate structures. In a previous study, a marked association between H....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
