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Article

Association of IFNGR2 gene polymorphisms with pulmonary tuberculosis among the Vietnamese.

Human genetics - 1 May 2012

Hijikata Minako, Shojima Junko, Matsushita Ikumi, Tokunaga Katsushi, Ohashi Jun, Hang Nguyen T L, Horie Toru, Sakurada Shinsaku, Hoang Nguyen P, Thuong Pham H, Lien Luu T, Keicho Naoto

Abstract excerpt

Interferon-γ (IFN-γ) is a key molecule of T helper 1 (Th1)-immune response against tuberculosis (TB), and rare genetic defects of IFN-γ receptors cause disseminated mycobacterial infection. The aim of the present study was to investigate whether genetic polymorphisms found in the Th1-immune response genes play a role in TB. In our study, DNA samples were collected from two series of cases including 832 patients...

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Source

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Identifiers

PMID: 22057826
DOI: 10.1007/s00439-011-1112-8
PMCID: PMC3325415

Genes

IFNGR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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