Article
Single nucleotide polymorphisms of IFNγ (+874 A/T) and IFNγR1 (-56 C/T) in Iranian patients with TB.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Dec 2016
Beiranvand Elham, Abediankenari Saeid, Valiyari Samira, Rezaei Mohammad Sadegh, Rostamian Mosayeb, Beiranvand Behnoush, Khaligh Ali, Khani Soghra
Abstract excerpt
BACKGROUND: Two important genes for controlling TB are IFNγ and IFNγR1. However, little information exists regarding genetic susceptibility of the Iranian TB population. METHODS: We investigated the single nucleotide polymorphisms (SNPs) in genes of IFNγ (+874 A/T) and IFNγR1 (-56 C/T) and serum level of IFNγ and their influence on TB in patients; 300 patients with TB and 300 healthy controls were enrolled in...
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