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Article

Contribution of cystatin C gene polymorphisms to cerebral white matter lesions.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2011

Mitaki Shingo, Nagai Atsushi, Sheikh Abdullah M, Terashima Masaharu, Isomura Minoru, Nabika Toru, Yamaguchi Shuhei

Abstract excerpt

BACKGROUND: Vascular remodeling plays an important role in the development of arteriosclerosis and any of the resulting white matter lesions in the brain. An imbalance between cysteine proteases and the cysteine protease inhibitor cystatin C (CST3) may exacerbate vascular remodeling through degradation of extracellular matrix proteins. Therefore, we evaluated the association between functional polymorphisms in...

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Identifiers

PMID: 22057131
DOI: 10.1159/000331921

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CST3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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