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MMP9 rs17576 Is Simultaneously Correlated with Symptomatic Intracranial Atherosclerotic Stenosis and White Matter Hyperintensities in Chinese Population.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2021

Feng Xianjing, Yu Fang, Zhou Xiaoqing, Liu Zeyu, Liao Di, Huang Qin, Li Xi, Jin Xin, Xia Jian

Abstract excerpt

PURPOSE: The aim of this study was screening for single nucleotide polymorphisms (SNPs) associated with white matter hyperintensities (WMHs) in symptomatic intracranial atherosclerotic stenosis (sICAS) patients and exploring a possible connection in the genetic background between macrovascular disease and small vessel disease. METHODS: There were 400 sICAS patients enrolled in the study. Fazekas scores were...

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PMID: 33296906
DOI: 10.1159/000511582

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